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This medicine is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, panic disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), social anxiety disorder (social phobia), and a severe form of premenstrual syndrome called premenstrual dysphoric disorder (PMDD).

Generic zoloft pill, a common antiparasitic for animals Treatment should include supportive care such as fluids, electrolytes, and supportive measures (for example, dressing, fluids, antibiotics) (see WARNINGS and PRECAUTIONS) In patients with severe acute disease or without fever, concomitant administration of chloroquine (if administered) may reduce the frequency of symptomatic seizures if the chloroquine dose is increased to approximately 150 mg/day Treatments for treatment-refractory epilepsies include a combination of lithium and anticonvulsants, intravenous benzodiazepines (such as alprazolam and diazepam), continuous-current electrical stimulation as an alternative for neurobehavioral therapy (see WARNINGS and CONCLUSIONS) Treatment of epileptic encephalopathies should be carefully monitored and treated in patients receiving high doses of benzodiazepines, because these medications may induce seizures (See DOSAGE AND ADMINISTRATION) Patients with acute seizure disorders should be carefully observed for convulsions and should be closely monitored for the development of extrapyramidal symptoms. Patients with moderate to severe seizure disorders must be regularly observed for the appearance of extrapyramidal symptoms. (See DOSAGE AND ADMINISTRATION) In patients with acute seizure disorders, including severe and refractory epilepsy, concomitant use of phenytoin hydrochloride and primidone may lead to an generic zoloft pill increased risk of acute liver failure (See WARNINGS) Clinical Studies Clinical studies of quetiapine are ongoing. In a randomized, placebo-controlled, double-blind study, tianeptine was superior to placebo in preventing relapses and improving function. In an open trial 22 pediatric patients with refractory unipolar major depressive disorder, quetiapine was superior to placebo at reducing depressive symptoms and improving behavior. The most recent placebo-controlled, double-blind study compared quetiapine 2.5 mg (n=26) to placebo (n=25). Quetiapine was more effective at preventing relapses and improving function. Two of the three major adverse events observed during the initial period of clinical studies were related to treatment with quetiapine, including dizziness, dizziness/vertigo, and insomnia. Dizziness/vertigo insomnia occurred equally frequently in the patients receiving quetiapine (0.3%; 13 studies) as in the patients receiving placebo (0.3%; 13 studies) (See ADVERSE REACTIONS). In another clinical study, which included a total of 779 subjects, seizures occurred in 5%, and caused discontinuation of treatment in 19% patients, compared with 30% in nonusers, and 29% patients taking placebo (see CLINICAL PHARMACOLOGY AND PHARMACOKINETICS). In combination with fluoxetine (5 to 15 mg daily) and sertraline (5 to 15 mg daily), there was a significantly increased risk of seizures when compared with placebo, a hazard ratio of 1.34 (95% confidence interval [CI] 1.08, 1.64). In the clinical trials described this report, serious or worsening reactions were common among patients receiving quetiapine. Serious or worsening reactions following quetiapine include: Anaphylactic reactions: Seizures have been reported in patients receiving quetiapine. Dose adjustments should be made in patients with seizure disorders. Seizures have been reported in patients receiving quetiapine. Dose adjustments should be made in patients with seizure disorders. Neurologic reactions: Seizures have occurred in patients receiving quetiapine. Dose adjustments should be made in patients with seizure disorders. Seizures have occurred in patients receiving quetiapine. Dose adjustments should be made in patients with seizure disorders. Abnormalities in cardiac conduction during activity: therapeutic doses, some cardiac conduction abnormalities of the cardiovascular system have been observed, including ventricular arrhythmias and atrial fibrillation, both of which have resulted in sudden death. Serious adverse cardiac events may also occur. Patients with a history of cardiac conduction abnormalities should be closely observed for events suggestive of cardiac conduction abnormalities before initiating or discontinuing therapy. In patients with epilepsy (with or without known concomitant cardiovascular disease), there have been isolated reports of abrupt death in association with use of quetiapine. The exact cause death is unknown, and it not possible to establish a causal relation between quetiapine and these events. The effect of quetiapine on risk sudden death has not been systematically studied.

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